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Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia

BACKGROUND AND OBJECTIVES: Chronic myeloid leukemia (CML) is characterized by hyperproliferation of myeloid precursors, increased fibrosis, and neoangiogenesis in the bone marrow. Imatinib inhibits BCR-ABL tyrosine kinase produced due to reciprocal translocation t(9;22) in neoplastic CML cells. It r...

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Detalles Bibliográficos
Autores principales:	Pandey, Neetu, Yadav, Geeta, Kushwaha, Rashmi, Verma, Shailendra Prasad, Singh, Uma Shankar, Kumar, Ashutosh, Mishra, Prabhaker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332991/ https://www.ncbi.nlm.nih.gov/pubmed/30713559 http://dx.doi.org/10.1155/2019/1835091

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