Cargando…

(18)F-FDG-PET Detects Drastic Changes in Brain Metabolism in the Tg4–42 Model of Alzheimer’s Disease

The evaluation of new therapeutic strategies in Alzheimer’s disease (AD) relies heavily on in vivo imaging and suitable animal models that mimic the pathological changes seen in patients. (18)F-Fluorodeoxyglucose ((18)F-FDG)-positron-emission tomography (PET) is a well-established non-invasive imagi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bouter, Caroline, Henniges, Philipp, Franke, Timon N., Irwin, Caroline, Sahlmann, Carsten Oliver, Sichler, Marius E., Beindorff, Nicola, Bayer, Thomas A., Bouter, Yvonne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333025/ https://www.ncbi.nlm.nih.gov/pubmed/30670962 http://dx.doi.org/10.3389/fnagi.2018.00425

Ejemplares similares

Analysis of Motor Function in the Tg4-42 Mouse Model of Alzheimer’s Disease
por: Wagner, Jannek M., et al.
Publicado: (2019)

In vivo Imaging With (18)F-FDG- and (18)F-Florbetaben-PET/MRI Detects Pathological Changes in the Brain of the Commonly Used 5XFAD Mouse Model of Alzheimer's Disease
por: Franke, Timon N., et al.
Publicado: (2020)

Reduced Acoustic Startle Response and Prepulse Inhibition in the Tg4-42 Model of Alzheimer’s Disease
por: Sichler, Marius E., et al.
Publicado: (2019)

Quantitative Brain Positron Emission Tomography in Female 5XFAD Alzheimer Mice: Pathological Features and Sex-Specific Alterations
por: Bouter, Caroline, et al.
Publicado: (2021)

(18)F-FDG-PET in Mouse Models of Alzheimer's Disease
por: Bouter, Caroline, et al.
Publicado: (2019)

Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits
por: Curdt, Nadine, et al.
Publicado: (2022)

miRNA Alterations Elicit Pathways Involved in Memory Decline and Synaptic Function in the Hippocampus of Aged Tg4-42 Mice
por: Bouter, Yvonne, et al.
Publicado: (2020)

(99m)Tc-Besilesomab-SPECT/CT in Infectious Endocarditis: Upgrade of a Forgotten Method?
por: Bouter, Caroline, et al.
Publicado: (2019)

Chronic exposure to a synthetic cannabinoid alters cerebral brain metabolism and causes long-lasting behavioral deficits in adult mice
por: Bouter, Caroline, et al.
Publicado: (2023)

Synaptic Alterations in Mouse Models for Alzheimer Disease—A Special Focus on N-Truncated Abeta 4-42
por: Dietrich, Katharina, et al.
Publicado: (2018)

Selective Serotonin Reuptake Inhibitor-Treatment Does Not Show Beneficial Effects on Cognition or Amyloid Burden in Cognitively Impaired and Cognitively Normal Subjects
por: Bouter, Yvonne, et al.
Publicado: (2022)

Prolonged Cannabidiol Treatment Lacks on Detrimental Effects on Memory, Motor Performance and Anxiety in C57BL/6J Mice
por: Schleicher, Eva M., et al.
Publicado: (2019)

Synergistic Effect on Neurodegeneration by N-Truncated Aβ(4−42) and Pyroglutamate Aβ(3−42) in a Mouse Model of Alzheimer's Disease
por: Lopez-Noguerola, Jose S., et al.
Publicado: (2018)

Abundance of Aβ(5-x) like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer’s disease
por: Guzmán, Erika Avendaño, et al.
Publicado: (2014)

Transgene integration causes RARB downregulation in homozygous Tg4–42 mice
por: Hinteregger, Barbara, et al.
Publicado: (2020)

Metabolic, Phenotypic, and Neuropathological Characterization of the Tg4-42 Mouse Model for Alzheimer’s Disease
por: Hinteregger, Barbara, et al.
Publicado: (2021)

N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits
por: Bouter, Yvonne, et al.
Publicado: (2013)

Case Report: Two Cases of Subacute Thyroiditis Following SARS-CoV-2 Vaccination
por: Bornemann, Catherine, et al.
Publicado: (2021)

Diagnostic Performance of (18)F-FDG PET/CT in Papillary Thyroid Carcinoma with Negative (131)I-WBS at first Postablation, Negative Tg and Progressively Increased TgAb Level
por: Qiu, Zhong-Ling, et al.
Publicado: (2017)

Alterations in androgen deprivation enhanced prostate-specific membrane antigen (PSMA) expression in prostate cancer cells as a target for diagnostics and therapy
por: Meller, B., et al.
Publicado: (2015)

A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease
por: Shahpasand-Kroner, Hedieh, et al.
Publicado: (2018)

The role of Tg kinetics in predicting 2-[(18)F]-FDG PET/CT results and overall survival in patients affected by differentiated thyroid carcinoma with detectable Tg and negative 131I-scan
por: Albano, Domenico, et al.
Publicado: (2021)

[(18)F]FAPI-42 PET/CT in differentiated thyroid cancer: diagnostic performance, uptake values, and comparison with 2-[(18)F]FDG PET/CT
por: Mu, Xingyu, et al.
Publicado: (2022)

Brain and Brown Adipose Tissue Metabolism in Transgenic Tg2576 Mice Models of Alzheimer Disease Assessed Using (18)F-FDG PET Imaging
por: Coleman, Robert A., et al.
Publicado: (2017)

Donanemab detects a minor fraction of amyloid-β plaques in post-mortem brain tissue of patients with Alzheimer’s disease and Down syndrome
por: Bouter, Yvonne, et al.
Publicado: (2022)

18-FDG PET in lung transplantation
por: Algieri, I, et al.
Publicado: (2015)

Myocarditis on (18)FDG-PET imaging
por: Chaaban, Nourhan, et al.
Publicado: (2022)

What Research Institutions Can Do to Foster Research Integrity
por: Bouter, Lex
Publicado: (2020)

Protective immunity induced by DNA vaccine containing TgGRA35, TgGRA42, and TgGRA43 against Toxoplasma gondii infection in Kunming mice
por: Shi, Youbo, et al.
Publicado: (2023)

Case Report: The Role of Neuropsychological Assessment and Imaging Biomarkers in the Early Diagnosis of Lewy Body Dementia in a Patient With Major Depression and Prolonged Alcohol and Benzodiazepine Dependence
por: Bouter, Caroline, et al.
Publicado: (2020)

Assessing Nigrostriatal Dopaminergic Pathways via 123I-FP-CIT SPECT in Dementia With Lewy Bodies in a Psychiatric Patient Cohort
por: Hansen, Niels, et al.
Publicado: (2021)

Delirium-Onset of Prodromal Dementia With Lewy Bodies—Putative Brainstem-Related Pathomechanism and Clinical Relevance
por: Hansen, Niels, et al.
Publicado: (2022)

Invited Commentary on “Investigating the Reliability and Factor Structure of Kalichman’s ‘Survey 2: Research Misconduct’ Questionnaire”
por: Bouter, Lex M.
Publicado: (2017)

PET probes beyond (18)F-FDG
por: Jiang, Lei, et al.
Publicado: (2014)

Feasibility of (18)FDG PET in the cardiac inflammation
por: Osiecki, Sebastian, et al.
Publicado: (2020)

Measurement Repeatability of (18)F-FDG PET/CT Versus (18)F-FDG PET/MRI in Solid Tumors of the Pelvis
por: Fraum, Tyler J., et al.
Publicado: (2019)

Whole-Body (18)FDG-PET in an Arthritis Paraneoplastic Syndrome Revealed an Underlying Hematological Neoplasm
por: Cammilleri, Serge, et al.
Publicado: (2013)

Reproducibility of Alzheimer’s Disease Cerebrospinal Fluid-Biomarker Measurements under Clinical Routine Conditions
por: Vogelgsang, Jonathan, et al.
Publicado: (2018)

Accuracy of [(18)F]FDG PET/MRI for the Detection of Liver Metastases
por: Beiderwellen, Karsten, et al.
Publicado: (2015)

CXCR4 PET imaging of mantle cell lymphoma using [(68)Ga]Pentixafor: comparison with [(18)F]FDG-PET
por: Mayerhoefer, Marius E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1pogmpr4m3lhc9fjblus5j62nn