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A Dual-Color Bioluminescence Reporter Mouse for Simultaneous in vivo Imaging of T Cell Localization and Function

Non-invasive imaging technologies to visualize the location and functionality of T cells are of great value in immunology. Here, we describe the design and generation of a transgenic mouse in which all T cells constitutively express green-emitting click-beetle luciferase (CBG99) while expression of...

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Detalles Bibliográficos
Autores principales:	Kleinovink, Jan Willem, Mezzanotte, Laura, Zambito, Giorgia, Fransen, Marieke F., Cruz, Luis J., Verbeek, J. Sjef, Chan, Alan, Ossendorp, Ferry, Löwik, Clemens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333049/ https://www.ncbi.nlm.nih.gov/pubmed/30671062 http://dx.doi.org/10.3389/fimmu.2018.03097

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