Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report

Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs‐negative hemolytic anemia combined with an increased LDH = Lactate dehydrogenase level are signs to test for PNH. Follow‐up does not need any microscopi...

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Detalles Bibliográficos
Autores principales: Elias, N.S., Riedl, Jürgen, Stouten, Karlijn, Levin, Mark‐David, Wolfhagen, Frank, Eefting, Mathijs, Vermeer, Henricus Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333074/
https://www.ncbi.nlm.nih.gov/pubmed/30656036
http://dx.doi.org/10.1002/ccr3.1771
Descripción
Sumario:Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs‐negative hemolytic anemia combined with an increased LDH = Lactate dehydrogenase level are signs to test for PNH. Follow‐up does not need any microscopic review's only flow cytometric PNH clone size.

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