Cargando…

Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report

Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs‐negative hemolytic anemia combined with an increased LDH = Lactate dehydrogenase level are signs to test for PNH. Follow‐up does not need any microscopi...

Descripción completa

Detalles Bibliográficos
Autores principales: Elias, N.S., Riedl, Jürgen, Stouten, Karlijn, Levin, Mark‐David, Wolfhagen, Frank, Eefting, Mathijs, Vermeer, Henricus Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333074/
https://www.ncbi.nlm.nih.gov/pubmed/30656036
http://dx.doi.org/10.1002/ccr3.1771
_version_ 1783387497315696640
author Elias, N.S.
Riedl, Jürgen
Stouten, Karlijn
Levin, Mark‐David
Wolfhagen, Frank
Eefting, Mathijs
Vermeer, Henricus Jan
author_facet Elias, N.S.
Riedl, Jürgen
Stouten, Karlijn
Levin, Mark‐David
Wolfhagen, Frank
Eefting, Mathijs
Vermeer, Henricus Jan
author_sort Elias, N.S.
collection PubMed
description Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs‐negative hemolytic anemia combined with an increased LDH = Lactate dehydrogenase level are signs to test for PNH. Follow‐up does not need any microscopic review's only flow cytometric PNH clone size.
format Online
Article
Text
id pubmed-6333074
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-63330742019-01-17 Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report Elias, N.S. Riedl, Jürgen Stouten, Karlijn Levin, Mark‐David Wolfhagen, Frank Eefting, Mathijs Vermeer, Henricus Jan Clin Case Rep Case Reports Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs‐negative hemolytic anemia combined with an increased LDH = Lactate dehydrogenase level are signs to test for PNH. Follow‐up does not need any microscopic review's only flow cytometric PNH clone size. John Wiley and Sons Inc. 2018-12-04 /pmc/articles/PMC6333074/ /pubmed/30656036 http://dx.doi.org/10.1002/ccr3.1771 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Elias, N.S.
Riedl, Jürgen
Stouten, Karlijn
Levin, Mark‐David
Wolfhagen, Frank
Eefting, Mathijs
Vermeer, Henricus Jan
Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report
title Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report
title_full Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report
title_fullStr Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report
title_full_unstemmed Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report
title_short Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report
title_sort abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333074/
https://www.ncbi.nlm.nih.gov/pubmed/30656036
http://dx.doi.org/10.1002/ccr3.1771
work_keys_str_mv AT eliasns abdominalpainincombinationwithanunexplainedhemolyticanemiaarecrucialsignstotestforparoxysmalnocturnalhemoglobinuriaacasereport
AT riedljurgen abdominalpainincombinationwithanunexplainedhemolyticanemiaarecrucialsignstotestforparoxysmalnocturnalhemoglobinuriaacasereport
AT stoutenkarlijn abdominalpainincombinationwithanunexplainedhemolyticanemiaarecrucialsignstotestforparoxysmalnocturnalhemoglobinuriaacasereport
AT levinmarkdavid abdominalpainincombinationwithanunexplainedhemolyticanemiaarecrucialsignstotestforparoxysmalnocturnalhemoglobinuriaacasereport
AT wolfhagenfrank abdominalpainincombinationwithanunexplainedhemolyticanemiaarecrucialsignstotestforparoxysmalnocturnalhemoglobinuriaacasereport
AT eeftingmathijs abdominalpainincombinationwithanunexplainedhemolyticanemiaarecrucialsignstotestforparoxysmalnocturnalhemoglobinuriaacasereport
AT vermeerhenricusjan abdominalpainincombinationwithanunexplainedhemolyticanemiaarecrucialsignstotestforparoxysmalnocturnalhemoglobinuriaacasereport