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Automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires
PURPOSE: The main objective of this study was to develop a technique to accurately determine the air gap between the end of the proton beam compensator and the body of the patient in proton radiotherapy. METHODS: Orthogonal x‐ray image‐based automatic coordinate reconstruction was used to determine...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333136/ https://www.ncbi.nlm.nih.gov/pubmed/30556259 http://dx.doi.org/10.1002/acm2.12509 |
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author | Ramesh, Pavitra Song, Wei Cao, Hongbin Zhao, Yanqun Parikh, Rahul Weiner, Joseph Wang, Xiao Nie, Ke Yue, Ning Zhang, Yin |
author_facet | Ramesh, Pavitra Song, Wei Cao, Hongbin Zhao, Yanqun Parikh, Rahul Weiner, Joseph Wang, Xiao Nie, Ke Yue, Ning Zhang, Yin |
author_sort | Ramesh, Pavitra |
collection | PubMed |
description | PURPOSE: The main objective of this study was to develop a technique to accurately determine the air gap between the end of the proton beam compensator and the body of the patient in proton radiotherapy. METHODS: Orthogonal x‐ray image‐based automatic coordinate reconstruction was used to determine the air gap between the patient body surface contour and the end of beam nozzle in proton radiotherapy. To be able to clearly identify the patient body surface contour on the orthogonal images, a radiopaque wire was placed on the skin surface of the patient as a surrogate. In order to validate this method, a Rando(®) head phantom was scanned and five proton plans were generated on a Mevion S250 Proton machine with various air gaps in Varian Eclipse Treatment Planning Systems (TPS). When setting up the phantom in a treatment room, a solder wire was placed on the surface of the phantom closest to the beam nozzle with the knowledge of the beam geometry in the plan. After the phantom positioning was verified using orthogonal kV imaging, the last pair of setup kV images was used to segment the solder wire and the in‐room coordinates of the wire were reconstructed using a back‐projection algorithm. Using the wire as a surrogate of the body surface, we calculated the air gaps by finding the minimum distance between the reconstructed wire and the end of the compensator. The methodology was also verified and validated on clinical cases. RESULTS: On the phantom study, the air gap values derived with the automatic reconstruction method were found to be within 1.1 mm difference from the planned values for proton beams with air gaps of 85.0, 100.0, 150.0, 180.0, and 200.0 mm. The reconstruction technique determined air gaps for a patient in two clinical treatment sessions were 38.4 and 41.8 mm, respectively, for a 40 mm planned air gap, and confirmed by manual measurements. There was strong agreement between the calculated values and the automatically measured values, and between the automatically and manually measured values. CONCLUSIONS: An image‐based automatic method has been developed to conveniently determine the air gap of a proton beam, directly using the orthogonal images for patient positioning without adding additional imaging dose to the patient. The method provides an objective, accurate, and efficient way to confirm the target depth at treatment to ensure desired target coverage and normal tissue sparing. |
format | Online Article Text |
id | pubmed-6333136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-63331362019-01-23 Automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires Ramesh, Pavitra Song, Wei Cao, Hongbin Zhao, Yanqun Parikh, Rahul Weiner, Joseph Wang, Xiao Nie, Ke Yue, Ning Zhang, Yin J Appl Clin Med Phys Technical Notes PURPOSE: The main objective of this study was to develop a technique to accurately determine the air gap between the end of the proton beam compensator and the body of the patient in proton radiotherapy. METHODS: Orthogonal x‐ray image‐based automatic coordinate reconstruction was used to determine the air gap between the patient body surface contour and the end of beam nozzle in proton radiotherapy. To be able to clearly identify the patient body surface contour on the orthogonal images, a radiopaque wire was placed on the skin surface of the patient as a surrogate. In order to validate this method, a Rando(®) head phantom was scanned and five proton plans were generated on a Mevion S250 Proton machine with various air gaps in Varian Eclipse Treatment Planning Systems (TPS). When setting up the phantom in a treatment room, a solder wire was placed on the surface of the phantom closest to the beam nozzle with the knowledge of the beam geometry in the plan. After the phantom positioning was verified using orthogonal kV imaging, the last pair of setup kV images was used to segment the solder wire and the in‐room coordinates of the wire were reconstructed using a back‐projection algorithm. Using the wire as a surrogate of the body surface, we calculated the air gaps by finding the minimum distance between the reconstructed wire and the end of the compensator. The methodology was also verified and validated on clinical cases. RESULTS: On the phantom study, the air gap values derived with the automatic reconstruction method were found to be within 1.1 mm difference from the planned values for proton beams with air gaps of 85.0, 100.0, 150.0, 180.0, and 200.0 mm. The reconstruction technique determined air gaps for a patient in two clinical treatment sessions were 38.4 and 41.8 mm, respectively, for a 40 mm planned air gap, and confirmed by manual measurements. There was strong agreement between the calculated values and the automatically measured values, and between the automatically and manually measured values. CONCLUSIONS: An image‐based automatic method has been developed to conveniently determine the air gap of a proton beam, directly using the orthogonal images for patient positioning without adding additional imaging dose to the patient. The method provides an objective, accurate, and efficient way to confirm the target depth at treatment to ensure desired target coverage and normal tissue sparing. John Wiley and Sons Inc. 2018-12-16 /pmc/articles/PMC6333136/ /pubmed/30556259 http://dx.doi.org/10.1002/acm2.12509 Text en © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Technical Notes Ramesh, Pavitra Song, Wei Cao, Hongbin Zhao, Yanqun Parikh, Rahul Weiner, Joseph Wang, Xiao Nie, Ke Yue, Ning Zhang, Yin Automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires |
title | Automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires |
title_full | Automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires |
title_fullStr | Automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires |
title_full_unstemmed | Automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires |
title_short | Automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires |
title_sort | automatic measurement of air gap for proton therapy using orthogonal x‐ray imaging with radiopaque wires |
topic | Technical Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333136/ https://www.ncbi.nlm.nih.gov/pubmed/30556259 http://dx.doi.org/10.1002/acm2.12509 |
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