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Effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial

PURPOSE: There is a general understanding that patient educational interventions for enhancing medication adherence are important. However, their success at improving adherence is debatable. This study aimed to assess the influence of different modes of patient education on medication adherence in p...

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Autores principales: Taibanguay, Nichapa, Chaiamnuay, Sumapa, Asavatanabodee, Paijit, Narongroeknawin, Pongthorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333161/
https://www.ncbi.nlm.nih.gov/pubmed/30666095
http://dx.doi.org/10.2147/PPA.S192008
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author Taibanguay, Nichapa
Chaiamnuay, Sumapa
Asavatanabodee, Paijit
Narongroeknawin, Pongthorn
author_facet Taibanguay, Nichapa
Chaiamnuay, Sumapa
Asavatanabodee, Paijit
Narongroeknawin, Pongthorn
author_sort Taibanguay, Nichapa
collection PubMed
description PURPOSE: There is a general understanding that patient educational interventions for enhancing medication adherence are important. However, their success at improving adherence is debatable. This study aimed to assess the influence of different modes of patient education on medication adherence in patients with rheumatoid arthritis (RA). MATERIALS AND METHODS: One hundred and twenty RA patients with non-adherence, defined as pill count ≥80% or medication-taking behavior questionnaire for Thai patient ≥23, were randomized by block randomization and assigned in a 1:1 allocation ratio to two study arms: multi-component intervention group or single intervention group. The multi-component intervention group received 30-minute directed counseling and a disease information pamphlet. The single intervention group received only a disease information pamphlet. The primary outcomes were an improvement in an adherence rate measured by pill count after 12 weeks. The Thai Clinical Trial Registry number is TCTR20171207003. RESULTS: After 12 weeks, the pill count adherence rate increased significantly from baseline in both study groups. In the multi-component intervention group, adherence rate increased from 92.21±14.05 to 97.59±10.07 (P=0.002) and in the single intervention group, it increased from 88.60±19.66 to 92.42±14.27 (P=0.044). However, the mean difference between the multi-component intervention group and the single intervention group was not significant (5.38±12.90 vs 3.18±14.23, P=0.531). Clinical outcomes, including disease activity score 28, EuroQoL-5D, EuroQol visual analog scale, pain score, and physician global assessment were unchanged from baseline in both groups. CONCLUSION: Patient education significantly improved adherence. However, there were no differences between single education intervention and multi-component education intervention in improving medication adherence. Provision of a disease information pamphlet with or without directed counseling can equally enhance medication adherence of patients with RA.
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spelling pubmed-63331612019-01-21 Effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial Taibanguay, Nichapa Chaiamnuay, Sumapa Asavatanabodee, Paijit Narongroeknawin, Pongthorn Patient Prefer Adherence Original Research PURPOSE: There is a general understanding that patient educational interventions for enhancing medication adherence are important. However, their success at improving adherence is debatable. This study aimed to assess the influence of different modes of patient education on medication adherence in patients with rheumatoid arthritis (RA). MATERIALS AND METHODS: One hundred and twenty RA patients with non-adherence, defined as pill count ≥80% or medication-taking behavior questionnaire for Thai patient ≥23, were randomized by block randomization and assigned in a 1:1 allocation ratio to two study arms: multi-component intervention group or single intervention group. The multi-component intervention group received 30-minute directed counseling and a disease information pamphlet. The single intervention group received only a disease information pamphlet. The primary outcomes were an improvement in an adherence rate measured by pill count after 12 weeks. The Thai Clinical Trial Registry number is TCTR20171207003. RESULTS: After 12 weeks, the pill count adherence rate increased significantly from baseline in both study groups. In the multi-component intervention group, adherence rate increased from 92.21±14.05 to 97.59±10.07 (P=0.002) and in the single intervention group, it increased from 88.60±19.66 to 92.42±14.27 (P=0.044). However, the mean difference between the multi-component intervention group and the single intervention group was not significant (5.38±12.90 vs 3.18±14.23, P=0.531). Clinical outcomes, including disease activity score 28, EuroQoL-5D, EuroQol visual analog scale, pain score, and physician global assessment were unchanged from baseline in both groups. CONCLUSION: Patient education significantly improved adherence. However, there were no differences between single education intervention and multi-component education intervention in improving medication adherence. Provision of a disease information pamphlet with or without directed counseling can equally enhance medication adherence of patients with RA. Dove Medical Press 2019-01-11 /pmc/articles/PMC6333161/ /pubmed/30666095 http://dx.doi.org/10.2147/PPA.S192008 Text en © 2019 Taibanguay et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Taibanguay, Nichapa
Chaiamnuay, Sumapa
Asavatanabodee, Paijit
Narongroeknawin, Pongthorn
Effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial
title Effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial
title_full Effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial
title_fullStr Effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial
title_full_unstemmed Effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial
title_short Effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial
title_sort effect of patient education on medication adherence of patients with rheumatoid arthritis: a randomized controlled trial
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333161/
https://www.ncbi.nlm.nih.gov/pubmed/30666095
http://dx.doi.org/10.2147/PPA.S192008
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