Cargando…

A dosimetric study on the use of 3D‐printed customized boluses in photon therapy: A hydrogel and silica gel study

PURPOSE: The aim of the study was to compare the dose differences between two kinds of materials (silica gel and hydrogel) used to prepare boluses based on three‐dimensional (3D) printing technologies and commercial bolus in head phantoms simulating nose, ear, and parotid gland radiotherapy. METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Yuehong, Yan, Tengfei, Sun, Yanze, Qian, Jianjun, Zhou, Gang, Cai, Shang, Tian, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333182/
https://www.ncbi.nlm.nih.gov/pubmed/30402935
http://dx.doi.org/10.1002/acm2.12489
_version_ 1783387518949916672
author Kong, Yuehong
Yan, Tengfei
Sun, Yanze
Qian, Jianjun
Zhou, Gang
Cai, Shang
Tian, Ye
author_facet Kong, Yuehong
Yan, Tengfei
Sun, Yanze
Qian, Jianjun
Zhou, Gang
Cai, Shang
Tian, Ye
author_sort Kong, Yuehong
collection PubMed
description PURPOSE: The aim of the study was to compare the dose differences between two kinds of materials (silica gel and hydrogel) used to prepare boluses based on three‐dimensional (3D) printing technologies and commercial bolus in head phantoms simulating nose, ear, and parotid gland radiotherapy. METHODS AND MATERIALS: We used 3D printing technology to make silica gel and hydrogel boluses. To evaluate the clinical feasibility, intensity modulated radiation therapy (IMRT) plans were created for head phantoms that were bolus‐free or had a commercial bolus, a silica gel bolus, or a hydrogel bolus. Dosimetry differences were compared in simulating nose, ear, and parotid gland radiotherapy separately. RESULTS: The air gaps were smaller in the silica gel and hydrogel bolus than the commercial one. In nose plans, it was shown that the V (95%) (relative volume that is covered by at least 95% of the prescription dose) of the silica gel (99.86%) and hydrogel (99.95%) bolus were better than the commercial one (98.39%) and bolus‐free (87.52%). Similarly, the homogeneity index (HI) and conformity index (CI) of the silica gel (0.06; 0.79) and hydrogel (0.058; 0.80) bolus were better than the commercial one (0.094; 0.72) and bolus‐free (0.59; 0.53). The parameters of results (HI, CI, V (95%)) were also better in 3D printing boluses than in the commercial bolus or without bolus in ear and parotid plans. CONCLUSIONS: Silica gel and hydrogel boluses were not only good for fit and a high level of comfort and repeatability, but also had better parameters in IMRT plans. They could replace the commercial bolus for clinical use.
format Online
Article
Text
id pubmed-6333182
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-63331822019-01-23 A dosimetric study on the use of 3D‐printed customized boluses in photon therapy: A hydrogel and silica gel study Kong, Yuehong Yan, Tengfei Sun, Yanze Qian, Jianjun Zhou, Gang Cai, Shang Tian, Ye J Appl Clin Med Phys Technical Notes PURPOSE: The aim of the study was to compare the dose differences between two kinds of materials (silica gel and hydrogel) used to prepare boluses based on three‐dimensional (3D) printing technologies and commercial bolus in head phantoms simulating nose, ear, and parotid gland radiotherapy. METHODS AND MATERIALS: We used 3D printing technology to make silica gel and hydrogel boluses. To evaluate the clinical feasibility, intensity modulated radiation therapy (IMRT) plans were created for head phantoms that were bolus‐free or had a commercial bolus, a silica gel bolus, or a hydrogel bolus. Dosimetry differences were compared in simulating nose, ear, and parotid gland radiotherapy separately. RESULTS: The air gaps were smaller in the silica gel and hydrogel bolus than the commercial one. In nose plans, it was shown that the V (95%) (relative volume that is covered by at least 95% of the prescription dose) of the silica gel (99.86%) and hydrogel (99.95%) bolus were better than the commercial one (98.39%) and bolus‐free (87.52%). Similarly, the homogeneity index (HI) and conformity index (CI) of the silica gel (0.06; 0.79) and hydrogel (0.058; 0.80) bolus were better than the commercial one (0.094; 0.72) and bolus‐free (0.59; 0.53). The parameters of results (HI, CI, V (95%)) were also better in 3D printing boluses than in the commercial bolus or without bolus in ear and parotid plans. CONCLUSIONS: Silica gel and hydrogel boluses were not only good for fit and a high level of comfort and repeatability, but also had better parameters in IMRT plans. They could replace the commercial bolus for clinical use. John Wiley and Sons Inc. 2018-11-07 /pmc/articles/PMC6333182/ /pubmed/30402935 http://dx.doi.org/10.1002/acm2.12489 Text en © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Notes
Kong, Yuehong
Yan, Tengfei
Sun, Yanze
Qian, Jianjun
Zhou, Gang
Cai, Shang
Tian, Ye
A dosimetric study on the use of 3D‐printed customized boluses in photon therapy: A hydrogel and silica gel study
title A dosimetric study on the use of 3D‐printed customized boluses in photon therapy: A hydrogel and silica gel study
title_full A dosimetric study on the use of 3D‐printed customized boluses in photon therapy: A hydrogel and silica gel study
title_fullStr A dosimetric study on the use of 3D‐printed customized boluses in photon therapy: A hydrogel and silica gel study
title_full_unstemmed A dosimetric study on the use of 3D‐printed customized boluses in photon therapy: A hydrogel and silica gel study
title_short A dosimetric study on the use of 3D‐printed customized boluses in photon therapy: A hydrogel and silica gel study
title_sort dosimetric study on the use of 3d‐printed customized boluses in photon therapy: a hydrogel and silica gel study
topic Technical Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333182/
https://www.ncbi.nlm.nih.gov/pubmed/30402935
http://dx.doi.org/10.1002/acm2.12489
work_keys_str_mv AT kongyuehong adosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT yantengfei adosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT sunyanze adosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT qianjianjun adosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT zhougang adosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT caishang adosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT tianye adosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT kongyuehong dosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT yantengfei dosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT sunyanze dosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT qianjianjun dosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT zhougang dosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT caishang dosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy
AT tianye dosimetricstudyontheuseof3dprintedcustomizedbolusesinphotontherapyahydrogelandsilicagelstudy