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Monte Carlo and analytic modeling of an Elekta Infinity linac with Agility MLC: Investigating the significance of accurate model parameters for small radiation fields

PURPOSE: To explain the deviation observed between measured and Monaco calculated dose profiles for a small field (i.e., alternating open‐closed MLC pattern). A Monte Carlo (MC) model of an Elekta Infinity linac with Agility MLC was created and validated against measurements. In addition, an analyti...

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Autores principales: Gholampourkashi, Sara, Cygler, Joanna E., Belec, Jason, Vujicic, Miro, Heath, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333188/
https://www.ncbi.nlm.nih.gov/pubmed/30408308
http://dx.doi.org/10.1002/acm2.12485
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author Gholampourkashi, Sara
Cygler, Joanna E.
Belec, Jason
Vujicic, Miro
Heath, Emily
author_facet Gholampourkashi, Sara
Cygler, Joanna E.
Belec, Jason
Vujicic, Miro
Heath, Emily
author_sort Gholampourkashi, Sara
collection PubMed
description PURPOSE: To explain the deviation observed between measured and Monaco calculated dose profiles for a small field (i.e., alternating open‐closed MLC pattern). A Monte Carlo (MC) model of an Elekta Infinity linac with Agility MLC was created and validated against measurements. In addition, an analytic model which predicts the fluence at the isocenter plane was used to study the impact of multiple beam parameters on the accuracy of dose calculations for small fields. METHODS: A detailed MC model of a 6 MV Elekta Infinity linac with Agility MLC was created in EGSnrc/BEAMnrc and validated against measurements. An analytic model using primary and secondary virtual photon sources was created and benchmarked against the MC simulations and the impact of multiple beam parameters on the accuracy of the model for a small field was investigated. Both models were used to explain discrepancies observed between measured/EGSnrc simulated and Monaco calculated dose profiles for alternating open‐closed MLC leaves. RESULTS: MC‐simulated dose profiles (PDDs, cross‐ and in‐line profiles, etc.) were found to be in very good agreements with measurements. The best fit for the leaf bank rotation was found to be 9 mrad to model the defocusing of Agility MLC. Moreover, a very good agreement was observed between results from the analytic model and MC simulations for a small field. Modifying the radial size of the incident electron beam in the BEAMnrc model improved the agreement between Monaco and EGSnrc calculated dose profiles by approximately 16% and 30% in the position of maxima and minima, respectively. CONCLUSION: Accurate modeling of the full‐width‐half‐maximum (FWHM) of the primary photon source as well as the MLC leaf design (leaf bank rotation, etc.) is essential for accurate calculations of dose delivered by small radiation fields when using virtual source or MC models of the beam.
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spelling pubmed-63331882019-01-23 Monte Carlo and analytic modeling of an Elekta Infinity linac with Agility MLC: Investigating the significance of accurate model parameters for small radiation fields Gholampourkashi, Sara Cygler, Joanna E. Belec, Jason Vujicic, Miro Heath, Emily J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: To explain the deviation observed between measured and Monaco calculated dose profiles for a small field (i.e., alternating open‐closed MLC pattern). A Monte Carlo (MC) model of an Elekta Infinity linac with Agility MLC was created and validated against measurements. In addition, an analytic model which predicts the fluence at the isocenter plane was used to study the impact of multiple beam parameters on the accuracy of dose calculations for small fields. METHODS: A detailed MC model of a 6 MV Elekta Infinity linac with Agility MLC was created in EGSnrc/BEAMnrc and validated against measurements. An analytic model using primary and secondary virtual photon sources was created and benchmarked against the MC simulations and the impact of multiple beam parameters on the accuracy of the model for a small field was investigated. Both models were used to explain discrepancies observed between measured/EGSnrc simulated and Monaco calculated dose profiles for alternating open‐closed MLC leaves. RESULTS: MC‐simulated dose profiles (PDDs, cross‐ and in‐line profiles, etc.) were found to be in very good agreements with measurements. The best fit for the leaf bank rotation was found to be 9 mrad to model the defocusing of Agility MLC. Moreover, a very good agreement was observed between results from the analytic model and MC simulations for a small field. Modifying the radial size of the incident electron beam in the BEAMnrc model improved the agreement between Monaco and EGSnrc calculated dose profiles by approximately 16% and 30% in the position of maxima and minima, respectively. CONCLUSION: Accurate modeling of the full‐width‐half‐maximum (FWHM) of the primary photon source as well as the MLC leaf design (leaf bank rotation, etc.) is essential for accurate calculations of dose delivered by small radiation fields when using virtual source or MC models of the beam. John Wiley and Sons Inc. 2018-11-08 /pmc/articles/PMC6333188/ /pubmed/30408308 http://dx.doi.org/10.1002/acm2.12485 Text en © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Gholampourkashi, Sara
Cygler, Joanna E.
Belec, Jason
Vujicic, Miro
Heath, Emily
Monte Carlo and analytic modeling of an Elekta Infinity linac with Agility MLC: Investigating the significance of accurate model parameters for small radiation fields
title Monte Carlo and analytic modeling of an Elekta Infinity linac with Agility MLC: Investigating the significance of accurate model parameters for small radiation fields
title_full Monte Carlo and analytic modeling of an Elekta Infinity linac with Agility MLC: Investigating the significance of accurate model parameters for small radiation fields
title_fullStr Monte Carlo and analytic modeling of an Elekta Infinity linac with Agility MLC: Investigating the significance of accurate model parameters for small radiation fields
title_full_unstemmed Monte Carlo and analytic modeling of an Elekta Infinity linac with Agility MLC: Investigating the significance of accurate model parameters for small radiation fields
title_short Monte Carlo and analytic modeling of an Elekta Infinity linac with Agility MLC: Investigating the significance of accurate model parameters for small radiation fields
title_sort monte carlo and analytic modeling of an elekta infinity linac with agility mlc: investigating the significance of accurate model parameters for small radiation fields
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333188/
https://www.ncbi.nlm.nih.gov/pubmed/30408308
http://dx.doi.org/10.1002/acm2.12485
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