Acute Dystonia Secondary to Domperidone in a Pediatric Patient

Domperidone is a dopamine-2 receptor (D2) antagonist. It is used as an antiemetic and has an excellent safety profile. We present a case of acute dystonia secondary to domperidone use in an 11-year-old girl. She was admitted with the diagnosis of viral gastroenteritis and received domperidone for pe...

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Autores principales: Shahbaz, Amir, Elahi, Karam, Affan, Muhammad, Shahid, Muhammad Faizan, Sabir, Ahtesham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333251/
https://www.ncbi.nlm.nih.gov/pubmed/30656090
http://dx.doi.org/10.7759/cureus.3587
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author Shahbaz, Amir
Elahi, Karam
Affan, Muhammad
Shahid, Muhammad Faizan
Sabir, Ahtesham
author_facet Shahbaz, Amir
Elahi, Karam
Affan, Muhammad
Shahid, Muhammad Faizan
Sabir, Ahtesham
author_sort Shahbaz, Amir
collection PubMed
description Domperidone is a dopamine-2 receptor (D2) antagonist. It is used as an antiemetic and has an excellent safety profile. We present a case of acute dystonia secondary to domperidone use in an 11-year-old girl. She was admitted with the diagnosis of viral gastroenteritis and received domperidone for persistent vomiting along with other supportive measures. The vomiting subsided with treatment, but she developed acute dystonia. Domperidone discontinued, and her condition improved in the next 24 hours. The patient discharged, and on a follow-up visit, she was asymptotic. A review of the literature suggests a possible association of acute dystonia with domperidone in children.
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spelling pubmed-63332512019-01-17 Acute Dystonia Secondary to Domperidone in a Pediatric Patient Shahbaz, Amir Elahi, Karam Affan, Muhammad Shahid, Muhammad Faizan Sabir, Ahtesham Cureus Neurology Domperidone is a dopamine-2 receptor (D2) antagonist. It is used as an antiemetic and has an excellent safety profile. We present a case of acute dystonia secondary to domperidone use in an 11-year-old girl. She was admitted with the diagnosis of viral gastroenteritis and received domperidone for persistent vomiting along with other supportive measures. The vomiting subsided with treatment, but she developed acute dystonia. Domperidone discontinued, and her condition improved in the next 24 hours. The patient discharged, and on a follow-up visit, she was asymptotic. A review of the literature suggests a possible association of acute dystonia with domperidone in children. Cureus 2018-11-13 /pmc/articles/PMC6333251/ /pubmed/30656090 http://dx.doi.org/10.7759/cureus.3587 Text en Copyright © 2018, Shahbaz et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Shahbaz, Amir
Elahi, Karam
Affan, Muhammad
Shahid, Muhammad Faizan
Sabir, Ahtesham
Acute Dystonia Secondary to Domperidone in a Pediatric Patient
title Acute Dystonia Secondary to Domperidone in a Pediatric Patient
title_full Acute Dystonia Secondary to Domperidone in a Pediatric Patient
title_fullStr Acute Dystonia Secondary to Domperidone in a Pediatric Patient
title_full_unstemmed Acute Dystonia Secondary to Domperidone in a Pediatric Patient
title_short Acute Dystonia Secondary to Domperidone in a Pediatric Patient
title_sort acute dystonia secondary to domperidone in a pediatric patient
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333251/
https://www.ncbi.nlm.nih.gov/pubmed/30656090
http://dx.doi.org/10.7759/cureus.3587
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AT shahidmuhammadfaizan acutedystoniasecondarytodomperidoneinapediatricpatient
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