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Structural studies of a surface-entropy reduction mutant of O-GlcNAcase

The enzyme O-GlcNAcase catalyses the removal of the O-GlcNAc co/post-translational modification in multicellular eukaryotes. The enzyme has become of acute interest given the intimate role of O-GlcNAcylation in tau modification and stability; small-molecular inhibitors of human O-GlcNAcase are under...

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Detalles Bibliográficos
Autores principales:	Males, Alexandra, Davies, Gideon J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2019
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333286/ https://www.ncbi.nlm.nih.gov/pubmed/30644846 http://dx.doi.org/10.1107/S2059798318016595

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