Identification of CMTM6 and CMTM4 as PD-L1 protein regulators

The clinical benefit in patients with diverse types of metastatic cancers that is observed upon blockade of the PD-1 – PD-L1 interaction has highlighted the importance of this inhibitory axis in the suppression of tumor-specific T cell responses1–9. In spite of the key role of PD-L1 expression by ce...

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Detalles Bibliográficos
Autores principales: Mezzadra, Riccardo, Sun, Chong, Jae, Lucas T., Gomez-Eerland, Raquel, de Vries, Evert, Wu, Wei, Logtenberg, Meike E.W., Slagter, Maarten, Rozeman, Elisa A., Hofland, Ingrid, Broeks, Annegien, Horlings, Hugo M., Wessels, Lodewyk F. A., Blank, Christian U., Xiao, Yanling, Heck, Albert J.R., Borst, Jannie, Brummelkamp, Thijn R., Schumacher, Ton N.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333292/
https://www.ncbi.nlm.nih.gov/pubmed/28813410
http://dx.doi.org/10.1038/nature23669

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