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Improvement of the CRISPR-Cpf1 system with ribozyme-processed crRNA

The recently discovered clustered regularly interspaced short palindromic repeats (CRISPR)-Cpf1 system expands the genome editing toolbox. This system exhibits several distinct features compared to the widely used CRISPR-Cas9 system, but has reduced gene editing efficiency. To optimize the CRISPR-Cp...

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Detalles Bibliográficos
Autores principales:	Gao, Zongliang, Herrera-Carrillo, Elena, Berkhout, Ben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333430/ https://www.ncbi.nlm.nih.gov/pubmed/30470168 http://dx.doi.org/10.1080/15476286.2018.1551703

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