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Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain
Tissue mechanics is important for development; however, the spatio-temporal dynamics of in vivo tissue stiffness is still poorly understood. We here developed tiv-AFM, combining time-lapse in vivo atomic force microscopy with upright fluorescence imaging of embryonic tissue, to show that during deve...
Autores principales: | Thompson, Amelia J, Pillai, Eva K, Dimov, Ivan B, Foster, Sarah K, Holt, Christine E, Franze, Kristian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333438/ https://www.ncbi.nlm.nih.gov/pubmed/30642430 http://dx.doi.org/10.7554/eLife.39356 |
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