Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons

Direct reprogramming of fibroblasts to neurons induces widespread cellular and transcriptional reconfiguration. Here, we characterized global epigenomic changes during the direct reprogramming of mouse fibroblasts to neurons using whole-genome base-resolution DNA methylation (mC) sequencing. We foun...

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Detalles Bibliográficos
Autores principales: Luo, Chongyuan, Lee, Qian Yi, Wapinski, Orly, Castanon, Rosa, Nery, Joseph R, Mall, Moritz, Kareta, Michael S, Cullen, Sean M, Goodell, Margaret A, Chang, Howard Y, Wernig, Marius, Ecker, Joseph R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333439/
https://www.ncbi.nlm.nih.gov/pubmed/30644360
http://dx.doi.org/10.7554/eLife.40197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333439/
https://www.ncbi.nlm.nih.gov/pubmed/30644360
http://dx.doi.org/10.7554/eLife.40197

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