Elevated CSF GAP-43 is Alzheimer’s disease specific and associated with tau and amyloid pathology

INTRODUCTION: The level of the presynaptic protein growth-associated protein 43 (GAP-43) in cerebrospinal fluid (CSF) has previously been shown to be increased in Alzheimer’s disease (AD) and thus may serve as an outcome measure in clinical trials and facilitate earlier disease detection. METHODS: W...

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Detalles Bibliográficos
Autores principales: Sandelius, Åsa, Portelius, Erik, Källén, Åsa, Zetterberg, Henrik, Rot, Uros, Olsson, Bob, Toledo, Jon B., Shaw, Leslie M., Lee, Virginia M. Y., Irwin, David J., Grossman, Murray, Weintraub, Daniel, Chen-Plotkin, Alice, Wolk, David A., McCluskey, Leo, Elman, Lauren, Kostanjevecki, Vesna, Vandijck, Manu, McBride, Jennifer, Trojanowski, John Q., Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333489/
https://www.ncbi.nlm.nih.gov/pubmed/30321501
http://dx.doi.org/10.1016/j.jalz.2018.08.006

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