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NME proteins regulate class switch recombination

Class switch recombination (CSR) in B cells involves deletion‐recombination at switch (S) region DNA and is important for the diversification of antibody isotypes during an immune response. Here, we identify two NME [NM23/NDPK (nucleoside diphosphate kinase)] isoforms, NME1 and NME2, as novel player...

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Detalles Bibliográficos
Autores principales: Zheng, Simin, Kusnadi, Anthony, Choi, Jee Eun, Vuong, Bao Q., Rhodes, Daniela, Chaudhuri, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333498/
https://www.ncbi.nlm.nih.gov/pubmed/30411342
http://dx.doi.org/10.1002/1873-3468.13290