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Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation
As the number of lung transplants performed worldwide each year continues to grow, the success of this procedure is threatened by the incidence of non-CMV infections such as invasive aspergillosis. Despite tremendous efforts and the availability of numerous diagnostic tests (especially in hematologi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333628/ https://www.ncbi.nlm.nih.gov/pubmed/30687264 http://dx.doi.org/10.3389/fmicb.2018.03273 |
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author | Herrera, Sabina Husain, Shahid |
author_facet | Herrera, Sabina Husain, Shahid |
author_sort | Herrera, Sabina |
collection | PubMed |
description | As the number of lung transplants performed worldwide each year continues to grow, the success of this procedure is threatened by the incidence of non-CMV infections such as invasive aspergillosis. Despite tremendous efforts and the availability of numerous diagnostic tests (especially in hematological malignancies) the diagnosis of invasive aspergillosis continues to be a challenge. Lung transplantation remains a unique clinical scenario, where additional host defenses are immunocompromized, making many of the available tests unsuitable. In this review we will navigate through the myriad of diagnostic tests currently available and how they apply to this unique patient population, as well as have a look into what the future holds. |
format | Online Article Text |
id | pubmed-6333628 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-63336282019-01-25 Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation Herrera, Sabina Husain, Shahid Front Microbiol Microbiology As the number of lung transplants performed worldwide each year continues to grow, the success of this procedure is threatened by the incidence of non-CMV infections such as invasive aspergillosis. Despite tremendous efforts and the availability of numerous diagnostic tests (especially in hematological malignancies) the diagnosis of invasive aspergillosis continues to be a challenge. Lung transplantation remains a unique clinical scenario, where additional host defenses are immunocompromized, making many of the available tests unsuitable. In this review we will navigate through the myriad of diagnostic tests currently available and how they apply to this unique patient population, as well as have a look into what the future holds. Frontiers Media S.A. 2019-01-09 /pmc/articles/PMC6333628/ /pubmed/30687264 http://dx.doi.org/10.3389/fmicb.2018.03273 Text en Copyright © 2019 Herrera and Husain. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Microbiology Herrera, Sabina Husain, Shahid Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation |
title | Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation |
title_full | Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation |
title_fullStr | Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation |
title_full_unstemmed | Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation |
title_short | Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation |
title_sort | current state of the diagnosis of invasive pulmonary aspergillosis in lung transplantation |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333628/ https://www.ncbi.nlm.nih.gov/pubmed/30687264 http://dx.doi.org/10.3389/fmicb.2018.03273 |
work_keys_str_mv | AT herrerasabina currentstateofthediagnosisofinvasivepulmonaryaspergillosisinlungtransplantation AT husainshahid currentstateofthediagnosisofinvasivepulmonaryaspergillosisinlungtransplantation |