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Ameliorating the Metabolic Burden of the Co-expression of Secreted Fungal Cellulases in a High Lipid-Accumulating Yarrowia lipolytica Strain by Medium C/N Ratio and a Chemical Chaperone
Yarrowia lipolytica, known to accumulate lipids intracellularly, lacks the cellulolytic enzymes needed to break down solid biomass directly. This study aimed to evaluate the potential metabolic burden of expressing core cellulolytic enzymes in an engineered high lipid-accumulating strain of Y. lipol...
Autores principales: | Wei, Hui, Wang, Wei, Alper, Hal S., Xu, Qi, Knoshaug, Eric P., Van Wychen, Stefanie, Lin, Chien-Yuan, Luo, Yonghua, Decker, Stephen R., Himmel, Michael E., Zhang, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333634/ https://www.ncbi.nlm.nih.gov/pubmed/30687267 http://dx.doi.org/10.3389/fmicb.2018.03276 |
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