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The Alteration of Subtelomeric DNA Methylation in Aging-Related Diseases

The telomere is located at the end of the chromosome and consists of a non-coding, repetitive DNA sequence. As the cell divides, the length of telomere gradually decreases. A very short telomere can terminate mitosis, and thus telomere length becomes a hallmark of cellular aging. The 500 kb region o...

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Detalles Bibliográficos
Autores principales: Hu, Haochang, Li, Bin, Duan, Shiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333653/
https://www.ncbi.nlm.nih.gov/pubmed/30687384
http://dx.doi.org/10.3389/fgene.2018.00697

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