Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report

Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency ane...

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Autores principales: Lee, Minhee, Kim, Tae Hee, Kim, Se Jeong, Jee, Byung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333760/
https://www.ncbi.nlm.nih.gov/pubmed/30671396
http://dx.doi.org/10.5468/ogs.2019.62.1.69
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author Lee, Minhee
Kim, Tae Hee
Kim, Se Jeong
Jee, Byung Chul
author_facet Lee, Minhee
Kim, Tae Hee
Kim, Se Jeong
Jee, Byung Chul
author_sort Lee, Minhee
collection PubMed
description Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency anemia. Brain magnetic resonance imaging showed high signal lesions in both occipital lobes on fluid-attenuated inversion-recovery (FLAIR) images, compatible with PRES. After treatment with anticonvulsant, she recovered both radiographically and clinically. The association between PRES and GnRH agonist use is still enigmatic, and thus should be further clarified.
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spelling pubmed-63337602019-01-22 Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report Lee, Minhee Kim, Tae Hee Kim, Se Jeong Jee, Byung Chul Obstet Gynecol Sci Case Report Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency anemia. Brain magnetic resonance imaging showed high signal lesions in both occipital lobes on fluid-attenuated inversion-recovery (FLAIR) images, compatible with PRES. After treatment with anticonvulsant, she recovered both radiographically and clinically. The association between PRES and GnRH agonist use is still enigmatic, and thus should be further clarified. Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society 2019-01 2018-12-03 /pmc/articles/PMC6333760/ /pubmed/30671396 http://dx.doi.org/10.5468/ogs.2019.62.1.69 Text en Copyright © 2019 Korean Society of Obstetrics and Gynecology http://creativecommons.org/licenses/by-nc/3.0/ Articles published in Obstet Gynecol Sci are open-access, distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Minhee
Kim, Tae Hee
Kim, Se Jeong
Jee, Byung Chul
Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_full Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_fullStr Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_full_unstemmed Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_short Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_sort posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333760/
https://www.ncbi.nlm.nih.gov/pubmed/30671396
http://dx.doi.org/10.5468/ogs.2019.62.1.69
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