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Breakdown of adaptive immunotolerance induces hepatocellular carcinoma in HBsAg-tg mice

Hepatitis B virus (HBV) can induce chronic inflammation, cirrhosis, and eventually hepatocellular carcinoma (HCC). Despite evidence suggesting a link between adaptive immunity and HBV-related diseases in humans, the immunopathogenic mechanisms involved are seldom described. Here we show that express...

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Detalles Bibliográficos
Autores principales:	Zong, Lu, Peng, Hui, Sun, Cheng, Li, Fenglei, Zheng, Meijuan, Chen, Yongyan, Wei, Haiming, Sun, Rui, Tian, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333806/ https://www.ncbi.nlm.nih.gov/pubmed/30644386 http://dx.doi.org/10.1038/s41467-018-08096-8

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