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Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice
Background: Idebenone is an antioxidant and a coenzyme Q10 analog that has been used to treat neurodegeneration disease. Some studies show idebenone exerts anti-inflammatory effects. However, whether idebenone can be used to reduce the neuroinflammation in Parkinson’s disease (PD) has been little st...
Autores principales: | Yan, Aijuan, Liu, Zhihua, Song, Lu, Wang, Xijin, Zhang, Yu, Wu, Na, Lin, Jingya, Liu, Ying, Liu, Zhenguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333870/ https://www.ncbi.nlm.nih.gov/pubmed/30687016 http://dx.doi.org/10.3389/fncel.2018.00529 |
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