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Analysis of α-Synuclein Pathology in PINK1 Knockout Rat Brains

Mutations in PTEN induced kinase 1 (PINK1) cause autosomal recessive Parkinson’s disease (PD). The main pathological hallmarks of PD are loss of dopaminergic neurons in the substantia nigra pars compacta and the formation of protein aggregates containing α-synuclein. Previous studies of PINK1 knocko...

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Detalles Bibliográficos
Autores principales:	Creed, Rose B., Goldberg, Matthew S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333903/ https://www.ncbi.nlm.nih.gov/pubmed/30686993 http://dx.doi.org/10.3389/fnins.2018.01034

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