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Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing

Trypanosome parasites control their virulence and spread by using quorum sensing (QS) to generate transmissible “stumpy forms” in their host bloodstream. However, the QS signal “stumpy induction factor” (SIF) and its reception mechanism are unknown. Although trypanosomes lack G protein-coupled recep...

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Detalles Bibliográficos
Autores principales: Rojas, Federico, Silvester, Eleanor, Young, Julie, Milne, Rachel, Tettey, Mabel, Houston, Douglas R., Walkinshaw, Malcolm D., Pérez-Pi, Irene, Auer, Manfred, Denton, Helen, Smith, Terry K., Thompson, Joanne, Matthews, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333907/
https://www.ncbi.nlm.nih.gov/pubmed/30503212
http://dx.doi.org/10.1016/j.cell.2018.10.041