Cargando…
Neurocysticercosis in a rural population with extensive pig production in Angónia district, Tete Province, Mozambique
Neurocysticercosis (NCC) is an important neurological disease in countries with high prevalence of Taenia solium infection and is emerging as a serious public health and economic problem. The aim of this study was to estimate the prevalence of NCC in Angónia district, Tete province, Mozambique based...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333921/ https://www.ncbi.nlm.nih.gov/pubmed/26519884 http://dx.doi.org/10.1016/j.actatropica.2015.10.018 |
_version_ | 1783387642882162688 |
---|---|
author | Assane, Yunus Amade Trevisan, Chiara Schutte, Clara Maria Noormahomed, Emilia Virginia Johansen, Maria Vang Magnussen, Pascal |
author_facet | Assane, Yunus Amade Trevisan, Chiara Schutte, Clara Maria Noormahomed, Emilia Virginia Johansen, Maria Vang Magnussen, Pascal |
author_sort | Assane, Yunus Amade |
collection | PubMed |
description | Neurocysticercosis (NCC) is an important neurological disease in countries with high prevalence of Taenia solium infection and is emerging as a serious public health and economic problem. The aim of this study was to estimate the prevalence of NCC in Angónia district, Tete province, Mozambique based on: prevalence of human T. solium cysticercosis assessed by antigen Enzyme-linked Immunosorbent Assay (Ag-ELISA) seropositivity, history of epilepsy, and brain computed tomography (CT) scan results. A cross sectional study was conducted between September and November 2007 in Angónia district. Questionnaires and blood samples were collected from 1,723 study subjects. Brain CT-scans were carried out on 151 study subjects with confirmed history of epilepsy. A total of 77 (51.0% (95% CI, 42.7–59.2)) and 38 (25.2% (95% CI, 18.5–32.9)) subjects met the criteria for definitive and probable diagnosis of NCC, respectively. T. solium Ag-ELISA seropositivity was found in 15.5% (95% CI, 12.8–16.2) of the study subjects. The estimated life time prevalence of epilepsy was 8.8% (95% CI, 7.5–10.2). Highly suggestive lesions of NCC were found on CT-scanning in 77 (71.9%, (95% CI, 62.4–80.2)) of the seropositive and 8 (18.1%, (95% CI, 8.2–32.7)) of the seronegative study subjects, respectively. The present findings revealed a high prevalence of NCC among people with epilepsy in Angónia district. Determination of effective strategies for prevention and control of T. solium cysticercosis are necessary to reduce the burden of NCC among the affected populations. |
format | Online Article Text |
id | pubmed-6333921 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
record_format | MEDLINE/PubMed |
spelling | pubmed-63339212019-01-16 Neurocysticercosis in a rural population with extensive pig production in Angónia district, Tete Province, Mozambique Assane, Yunus Amade Trevisan, Chiara Schutte, Clara Maria Noormahomed, Emilia Virginia Johansen, Maria Vang Magnussen, Pascal Acta Trop Article Neurocysticercosis (NCC) is an important neurological disease in countries with high prevalence of Taenia solium infection and is emerging as a serious public health and economic problem. The aim of this study was to estimate the prevalence of NCC in Angónia district, Tete province, Mozambique based on: prevalence of human T. solium cysticercosis assessed by antigen Enzyme-linked Immunosorbent Assay (Ag-ELISA) seropositivity, history of epilepsy, and brain computed tomography (CT) scan results. A cross sectional study was conducted between September and November 2007 in Angónia district. Questionnaires and blood samples were collected from 1,723 study subjects. Brain CT-scans were carried out on 151 study subjects with confirmed history of epilepsy. A total of 77 (51.0% (95% CI, 42.7–59.2)) and 38 (25.2% (95% CI, 18.5–32.9)) subjects met the criteria for definitive and probable diagnosis of NCC, respectively. T. solium Ag-ELISA seropositivity was found in 15.5% (95% CI, 12.8–16.2) of the study subjects. The estimated life time prevalence of epilepsy was 8.8% (95% CI, 7.5–10.2). Highly suggestive lesions of NCC were found on CT-scanning in 77 (71.9%, (95% CI, 62.4–80.2)) of the seropositive and 8 (18.1%, (95% CI, 8.2–32.7)) of the seronegative study subjects, respectively. The present findings revealed a high prevalence of NCC among people with epilepsy in Angónia district. Determination of effective strategies for prevention and control of T. solium cysticercosis are necessary to reduce the burden of NCC among the affected populations. 2015-10-28 2017-01 /pmc/articles/PMC6333921/ /pubmed/26519884 http://dx.doi.org/10.1016/j.actatropica.2015.10.018 Text en This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Assane, Yunus Amade Trevisan, Chiara Schutte, Clara Maria Noormahomed, Emilia Virginia Johansen, Maria Vang Magnussen, Pascal Neurocysticercosis in a rural population with extensive pig production in Angónia district, Tete Province, Mozambique |
title | Neurocysticercosis in a rural population with extensive pig production in Angónia district, Tete Province, Mozambique |
title_full | Neurocysticercosis in a rural population with extensive pig production in Angónia district, Tete Province, Mozambique |
title_fullStr | Neurocysticercosis in a rural population with extensive pig production in Angónia district, Tete Province, Mozambique |
title_full_unstemmed | Neurocysticercosis in a rural population with extensive pig production in Angónia district, Tete Province, Mozambique |
title_short | Neurocysticercosis in a rural population with extensive pig production in Angónia district, Tete Province, Mozambique |
title_sort | neurocysticercosis in a rural population with extensive pig production in angónia district, tete province, mozambique |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333921/ https://www.ncbi.nlm.nih.gov/pubmed/26519884 http://dx.doi.org/10.1016/j.actatropica.2015.10.018 |
work_keys_str_mv | AT assaneyunusamade neurocysticercosisinaruralpopulationwithextensivepigproductioninangoniadistrictteteprovincemozambique AT trevisanchiara neurocysticercosisinaruralpopulationwithextensivepigproductioninangoniadistrictteteprovincemozambique AT schutteclaramaria neurocysticercosisinaruralpopulationwithextensivepigproductioninangoniadistrictteteprovincemozambique AT noormahomedemiliavirginia neurocysticercosisinaruralpopulationwithextensivepigproductioninangoniadistrictteteprovincemozambique AT johansenmariavang neurocysticercosisinaruralpopulationwithextensivepigproductioninangoniadistrictteteprovincemozambique AT magnussenpascal neurocysticercosisinaruralpopulationwithextensivepigproductioninangoniadistrictteteprovincemozambique |