Ginsenosides Act As Positive Modulators of P2X4 Receptors

We investigated the selectivity of protopanaxadiol ginsenosides from Panax ginseng acting as positive allosteric modulators on P2X receptors. ATP-induced responses were measured in stable cell lines overexpressing human P2X4 using a YOPRO-1 dye uptake assay, intracellular calcium measurements, and w...

Descripción completa

Detalles Bibliográficos
Autores principales: Dhuna, Kshitija, Felgate, Matthew, Bidula, Stefan M., Walpole, Samuel, Bibic, Lucka, Cromer, Brett A., Angulo, Jesus, Sanderson, Julie, Stebbing, Martin J., Stokes, Leanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334005/
https://www.ncbi.nlm.nih.gov/pubmed/30545933
http://dx.doi.org/10.1124/mol.118.113696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334005/
https://www.ncbi.nlm.nih.gov/pubmed/30545933
http://dx.doi.org/10.1124/mol.118.113696

Ejemplares similares