Human Enzymes for Organic Synthesis

Human enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that catalyze chemical reactions in course of the metabolism...

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Detalles Bibliográficos
Autores principales: Winkler, Margit, Geier, Martina, Hanlon, Steven P., Nidetzky, Bernd, Glieder, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334177/
https://www.ncbi.nlm.nih.gov/pubmed/29600541
http://dx.doi.org/10.1002/anie.201800678
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author Winkler, Margit
Geier, Martina
Hanlon, Steven P.
Nidetzky, Bernd
Glieder, Anton
author_facet Winkler, Margit
Geier, Martina
Hanlon, Steven P.
Nidetzky, Bernd
Glieder, Anton
author_sort Winkler, Margit
collection PubMed
description Human enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that catalyze chemical reactions in course of the metabolism of drugs and xenobiotics. Some of these reactions have been explored on the preparative scale. The major field of application of human enzymes is currently drug development, where they are applied for the synthesis of drug metabolites.
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spelling pubmed-63341772019-01-23 Human Enzymes for Organic Synthesis Winkler, Margit Geier, Martina Hanlon, Steven P. Nidetzky, Bernd Glieder, Anton Angew Chem Int Ed Engl Reviews Human enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that catalyze chemical reactions in course of the metabolism of drugs and xenobiotics. Some of these reactions have been explored on the preparative scale. The major field of application of human enzymes is currently drug development, where they are applied for the synthesis of drug metabolites. John Wiley and Sons Inc. 2018-09-11 2018-10-08 /pmc/articles/PMC6334177/ /pubmed/29600541 http://dx.doi.org/10.1002/anie.201800678 Text en © 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Winkler, Margit
Geier, Martina
Hanlon, Steven P.
Nidetzky, Bernd
Glieder, Anton
Human Enzymes for Organic Synthesis
title Human Enzymes for Organic Synthesis
title_full Human Enzymes for Organic Synthesis
title_fullStr Human Enzymes for Organic Synthesis
title_full_unstemmed Human Enzymes for Organic Synthesis
title_short Human Enzymes for Organic Synthesis
title_sort human enzymes for organic synthesis
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334177/
https://www.ncbi.nlm.nih.gov/pubmed/29600541
http://dx.doi.org/10.1002/anie.201800678
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