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Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review

OBJECTIVE: To investigate the prevalence of financial interests among patient organisations contributing to health technology assessment at the National Institute for Health and Care Excellence (NICE) in England and the extent to which NICE’s disclosure policy ensures that decision making committees...

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Autores principales: Mandeville, Kate L, Barker, Rosie, Packham, Alice, Sowerby, Charlotte, Yarrow, Kielan, Patrick, Hannah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334181/
https://www.ncbi.nlm.nih.gov/pubmed/30651227
http://dx.doi.org/10.1136/bmj.k5300
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author Mandeville, Kate L
Barker, Rosie
Packham, Alice
Sowerby, Charlotte
Yarrow, Kielan
Patrick, Hannah
author_facet Mandeville, Kate L
Barker, Rosie
Packham, Alice
Sowerby, Charlotte
Yarrow, Kielan
Patrick, Hannah
author_sort Mandeville, Kate L
collection PubMed
description OBJECTIVE: To investigate the prevalence of financial interests among patient organisations contributing to health technology assessment at the National Institute for Health and Care Excellence (NICE) in England and the extent to which NICE’s disclosure policy ensures that decision making committees are aware of these interests. DESIGN: Policy review using accounts, annual reports, and websites of patient organisations; payments declared by pharmaceutical manufacturers on their websites and a centralised database (Disclosure UK); declarations of interests by nominated representatives of patient organisations; and responses from patient organisations. SETTING: Appraisals of medicines and treatments (technologies) for use in the English and Welsh National Health Service. PARTICIPANTS: 53 patient organisations contributing to 41 NICE technology appraisals published in 2015 and 2016, with 117 separate occasions that a patient organisation contributed to the appraisal of a technology. MAIN OUTCOME MEASURES: Prevalence of specific interests (that is, funding from manufacturer(s) of a technology under appraisal or competitor products); proportion of specific interests of which NICE’s decision making committees were aware; proportion of unknown specific interests for which disclosure was not required by NICE’s policy RESULTS: 38/53 (72%) patient organisations had accepted funding from the manufacturer(s) of a technology or a competitor product in the same year that they had contributed to the appraisal of that technology or the previous year. Specific interests were present on 92/117 (79%) occasions that patient organisations contributed to appraisals in 2015 and 2016. NICE’s decision making committees were aware of less than a quarter of specific interests (30/144; 21%). For nearly two thirds of the specific interests not known to committees (71/114; 62%), disclosure by patient organisations was not required by NICE’s policy. CONCLUSIONS: Financial interests are highly prevalent among patient organisations contributing to health technology assessment. NICE should review its disclosure policy to ensure that decision making committees are aware of all relevant interests.
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spelling pubmed-63341812019-01-27 Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review Mandeville, Kate L Barker, Rosie Packham, Alice Sowerby, Charlotte Yarrow, Kielan Patrick, Hannah BMJ Research OBJECTIVE: To investigate the prevalence of financial interests among patient organisations contributing to health technology assessment at the National Institute for Health and Care Excellence (NICE) in England and the extent to which NICE’s disclosure policy ensures that decision making committees are aware of these interests. DESIGN: Policy review using accounts, annual reports, and websites of patient organisations; payments declared by pharmaceutical manufacturers on their websites and a centralised database (Disclosure UK); declarations of interests by nominated representatives of patient organisations; and responses from patient organisations. SETTING: Appraisals of medicines and treatments (technologies) for use in the English and Welsh National Health Service. PARTICIPANTS: 53 patient organisations contributing to 41 NICE technology appraisals published in 2015 and 2016, with 117 separate occasions that a patient organisation contributed to the appraisal of a technology. MAIN OUTCOME MEASURES: Prevalence of specific interests (that is, funding from manufacturer(s) of a technology under appraisal or competitor products); proportion of specific interests of which NICE’s decision making committees were aware; proportion of unknown specific interests for which disclosure was not required by NICE’s policy RESULTS: 38/53 (72%) patient organisations had accepted funding from the manufacturer(s) of a technology or a competitor product in the same year that they had contributed to the appraisal of that technology or the previous year. Specific interests were present on 92/117 (79%) occasions that patient organisations contributed to appraisals in 2015 and 2016. NICE’s decision making committees were aware of less than a quarter of specific interests (30/144; 21%). For nearly two thirds of the specific interests not known to committees (71/114; 62%), disclosure by patient organisations was not required by NICE’s policy. CONCLUSIONS: Financial interests are highly prevalent among patient organisations contributing to health technology assessment. NICE should review its disclosure policy to ensure that decision making committees are aware of all relevant interests. BMJ Publishing Group Ltd. 2019-01-16 /pmc/articles/PMC6334181/ /pubmed/30651227 http://dx.doi.org/10.1136/bmj.k5300 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Research
Mandeville, Kate L
Barker, Rosie
Packham, Alice
Sowerby, Charlotte
Yarrow, Kielan
Patrick, Hannah
Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review
title Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review
title_full Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review
title_fullStr Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review
title_full_unstemmed Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review
title_short Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review
title_sort financial interests of patient organisations contributing to technology assessment at england’s national institute for health and care excellence: policy review
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334181/
https://www.ncbi.nlm.nih.gov/pubmed/30651227
http://dx.doi.org/10.1136/bmj.k5300
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