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The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection
Cryptococcal infection results from inhalation of fungal spores and usually is confined to the lungs, but may disseminate systemically. Radiologically, cryptococcal infection has multiple forms of presentation. The diagnosis is usually based on fungal isolation from cultured clinical specimens. Long...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334315/ https://www.ncbi.nlm.nih.gov/pubmed/30719369 http://dx.doi.org/10.1155/2019/5970648 |
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author | Barbosa De Araujo Neto, Francisco Corona De Godoy Bueno, Camila Tambelini Gomes, Liege Alejandra Ortiz Navas, Daniela Wanderley, Mark Gallotti Borges Carneiro, Stefanie Karine Veras Gomes De Mello, Rita Mendes Coura, Laura Sayuri Missumi, Larissa Durante, Henrique Cintra Zagatti, Ricardo Francisco Sawamura, Márcio Valente Yamada |
author_facet | Barbosa De Araujo Neto, Francisco Corona De Godoy Bueno, Camila Tambelini Gomes, Liege Alejandra Ortiz Navas, Daniela Wanderley, Mark Gallotti Borges Carneiro, Stefanie Karine Veras Gomes De Mello, Rita Mendes Coura, Laura Sayuri Missumi, Larissa Durante, Henrique Cintra Zagatti, Ricardo Francisco Sawamura, Márcio Valente Yamada |
author_sort | Barbosa De Araujo Neto, Francisco |
collection | PubMed |
description | Cryptococcal infection results from inhalation of fungal spores and usually is confined to the lungs, but may disseminate systemically. Radiologically, cryptococcal infection has multiple forms of presentation. The diagnosis is usually based on fungal isolation from cultured clinical specimens. Long term antifungal therapy is recommended, but surgical procedures may eventually be necessary when large thoracic symptomatic masses are present. We report a case of a 41-year-old male, immunocompetent, investigating a palpable mass in the left supraclavicular region associated with unintentional weight loss over the last three months. He also reported chest pain in this period. Chest X-ray, ultrasonography, and computed tomography were performed, which diagnosed a mediastinal and left supraclavicular mass, interpreted as lymph node conglomerates of unknown etiology. He also underwent a biopsy of the left supraclavicular mass for etiological determination by histopathology, which confirmed cryptococcosis infection. Although very infrequent, mediastinal cryptococcal infection (simulating masses) is a challenging but important differential diagnosis of benign and malignant lesions, since its treatment is usually clinical. |
format | Online Article Text |
id | pubmed-6334315 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-63343152019-02-04 The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection Barbosa De Araujo Neto, Francisco Corona De Godoy Bueno, Camila Tambelini Gomes, Liege Alejandra Ortiz Navas, Daniela Wanderley, Mark Gallotti Borges Carneiro, Stefanie Karine Veras Gomes De Mello, Rita Mendes Coura, Laura Sayuri Missumi, Larissa Durante, Henrique Cintra Zagatti, Ricardo Francisco Sawamura, Márcio Valente Yamada Case Rep Radiol Case Report Cryptococcal infection results from inhalation of fungal spores and usually is confined to the lungs, but may disseminate systemically. Radiologically, cryptococcal infection has multiple forms of presentation. The diagnosis is usually based on fungal isolation from cultured clinical specimens. Long term antifungal therapy is recommended, but surgical procedures may eventually be necessary when large thoracic symptomatic masses are present. We report a case of a 41-year-old male, immunocompetent, investigating a palpable mass in the left supraclavicular region associated with unintentional weight loss over the last three months. He also reported chest pain in this period. Chest X-ray, ultrasonography, and computed tomography were performed, which diagnosed a mediastinal and left supraclavicular mass, interpreted as lymph node conglomerates of unknown etiology. He also underwent a biopsy of the left supraclavicular mass for etiological determination by histopathology, which confirmed cryptococcosis infection. Although very infrequent, mediastinal cryptococcal infection (simulating masses) is a challenging but important differential diagnosis of benign and malignant lesions, since its treatment is usually clinical. Hindawi 2019-01-02 /pmc/articles/PMC6334315/ /pubmed/30719369 http://dx.doi.org/10.1155/2019/5970648 Text en Copyright © 2019 Francisco Barbosa De Araujo Neto et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Barbosa De Araujo Neto, Francisco Corona De Godoy Bueno, Camila Tambelini Gomes, Liege Alejandra Ortiz Navas, Daniela Wanderley, Mark Gallotti Borges Carneiro, Stefanie Karine Veras Gomes De Mello, Rita Mendes Coura, Laura Sayuri Missumi, Larissa Durante, Henrique Cintra Zagatti, Ricardo Francisco Sawamura, Márcio Valente Yamada The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
title | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
title_full | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
title_fullStr | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
title_full_unstemmed | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
title_short | The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection |
title_sort | diagnostic challenge of an infrequent spectrum of cryptococcus infection |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334315/ https://www.ncbi.nlm.nih.gov/pubmed/30719369 http://dx.doi.org/10.1155/2019/5970648 |
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