Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis

An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL(−1). Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7...

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Autores principales: Pedroso, Tahisa Marcela, Schepdael, Ann Van, Salgado, Hérida Regina Nunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334326/
https://www.ncbi.nlm.nih.gov/pubmed/30719040
http://dx.doi.org/10.1155/2019/1456313
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author Pedroso, Tahisa Marcela
Schepdael, Ann Van
Salgado, Hérida Regina Nunes
author_facet Pedroso, Tahisa Marcela
Schepdael, Ann Van
Salgado, Hérida Regina Nunes
author_sort Pedroso, Tahisa Marcela
collection PubMed
description An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL(−1). Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x - 24495 with a R(2) = 0.9994. Thus, we propose a routine analysis method that meets the principles of green analytical chemistry for the routine analysis of ertapenem sodium by capillary electrophoresis.
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spelling pubmed-63343262019-02-04 Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis Pedroso, Tahisa Marcela Schepdael, Ann Van Salgado, Hérida Regina Nunes Int J Anal Chem Research Article An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL(−1). Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x - 24495 with a R(2) = 0.9994. Thus, we propose a routine analysis method that meets the principles of green analytical chemistry for the routine analysis of ertapenem sodium by capillary electrophoresis. Hindawi 2019-01-02 /pmc/articles/PMC6334326/ /pubmed/30719040 http://dx.doi.org/10.1155/2019/1456313 Text en Copyright © 2019 Tahisa Marcela Pedroso et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Pedroso, Tahisa Marcela
Schepdael, Ann Van
Salgado, Hérida Regina Nunes
Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_full Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_fullStr Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_full_unstemmed Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_short Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_sort application of the principles of green chemistry for the development of a new and sensitive method for analysis of ertapenem sodium by capillary electrophoresis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334326/
https://www.ncbi.nlm.nih.gov/pubmed/30719040
http://dx.doi.org/10.1155/2019/1456313
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