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Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial
BACKGROUND: Gabapentin has shown efficacy in the treatment of chronic neuropathic or mixed pain in adults. Although pediatric pain specialists have extensive experience with gabapentin for the treatment of neuropathic pain, its use is off-label. Its efficacy and safety in this context have never bee...
Autores principales: | de Leeuw, Thomas G., Mangiarini, Laura, Lundin, Rebecca, Kaguelidou, Florentia, van der Zanden, Tjitske, Pasqua, Oscar Della, Tibboel, Dick, Ceci, Adriana, de Wildt, Saskia N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334401/ https://www.ncbi.nlm.nih.gov/pubmed/30646965 http://dx.doi.org/10.1186/s13063-018-3169-3 |
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