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Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases

BACKGROUND: Non-human primate (NHP) models can closely mimic human physiological functions and are therefore highly valuable in biomedical research. Genome editing is now developing rapidly due to the precision and efficiency offered by engineered site-specific endonuclease-based systems, such as tr...

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Detalles Bibliográficos
Autores principales:	Chu, Chu, Yang, Zhaohui, Yang, Jiayin, Yan, Li, Si, Chenyang, Kang, Yu, Chen, Zhenzhen, Chen, Yongchang, Ji, Weizhi, Niu, Yuyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334428/ https://www.ncbi.nlm.nih.gov/pubmed/30646876 http://dx.doi.org/10.1186/s12896-018-0494-2

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