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Genistein inhibits stemness of SKOV3 cells induced by macrophages co-cultured with ovarian cancer stem-like cells through IL-8/STAT3 axis
BACKGROUND: Recent studies showed that macrophages co-cultured with ovarian cancer stem-like cells (OCSLCs) induced SKOV3 cell stemness via IL-8/STAT3 signaling. Genistein (GEN) demonstrates chemopreventive activity in inflammation-associated cancers. The present study aimed to examine whether and i...
Autores principales: | Ning, Yingxia, Feng, Weifeng, Cao, Xiaocheng, Ren, Kaiqun, Quan, Meifang, Chen, A., Xu, Chang, Qiu, Yebei, Cao, Jianguo, Li, Xiang, Luo, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334437/ https://www.ncbi.nlm.nih.gov/pubmed/30646963 http://dx.doi.org/10.1186/s13046-018-1010-1 |
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