The MTHFR promoter hypermethylation pattern associated with the A1298C polymorphism influences lipid parameters and glycemic control in diabetic patients

BACKGROUND: Polymorphisms in the gene encoding methylenetetrahydrofolate reductase (MTHFR) have been investigated as risk factors for microvascular complications of diabetes; however, simultaneous analysis of these polymorphisms and the methylation pattern of the gene has never been conducted. The o...

Descripción completa

Detalles Bibliográficos
Autores principales: Santana Bezerra, Herlanny, Severo de Assis, Caroline, dos Santos Nunes, Mayara Karla, Wanderley de Queiroga Evangelista, Isabella, Modesto Filho, João, Alves Pegado Gomes, Cecília Neta, Ferreira do Nascimento, Rayner Anderson, Pordeus Luna, Rafaella Cristhine, de Carvalho Costa, Maria José, de Oliveira, Naila Francis Paulo, Camati Persuhn, Darlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334445/
https://www.ncbi.nlm.nih.gov/pubmed/30675189
http://dx.doi.org/10.1186/s13098-019-0399-9

Ejemplares similares

Ejemplares similares