An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children

Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10–15 years. Overall, our findings reveal the importance of different g...

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Detalles Bibliográficos
Autores principales: Sottile, Gianluca, Ferrante, Giuliana, Torregrossa, Marta, Cibella, Fabio, Cilluffo, Giovanna, Fasola, Salvatore, Alessandro, Riccardo, Seidita, Gregorio, Viegi, Giovanni, La Grutta, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334451/
https://www.ncbi.nlm.nih.gov/pubmed/30646946
http://dx.doi.org/10.1186/s13052-019-0603-4
Descripción
Sumario:Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10–15 years. Overall, our findings reveal the importance of different genetic variants at 4p14, 16p12.1, 17q12, 6p12.2 and 17q21.1, identifying possible candidate genes responsible for susceptibility to asthma and rhino-conjunctivitis.

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