An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children

Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10–15 years. Overall, our findings reveal the importance of different g...

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Autores principales: Sottile, Gianluca, Ferrante, Giuliana, Torregrossa, Marta, Cibella, Fabio, Cilluffo, Giovanna, Fasola, Salvatore, Alessandro, Riccardo, Seidita, Gregorio, Viegi, Giovanni, La Grutta, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334451/
https://www.ncbi.nlm.nih.gov/pubmed/30646946
http://dx.doi.org/10.1186/s13052-019-0603-4
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author Sottile, Gianluca
Ferrante, Giuliana
Torregrossa, Marta
Cibella, Fabio
Cilluffo, Giovanna
Fasola, Salvatore
Alessandro, Riccardo
Seidita, Gregorio
Viegi, Giovanni
La Grutta, Stefania
author_facet Sottile, Gianluca
Ferrante, Giuliana
Torregrossa, Marta
Cibella, Fabio
Cilluffo, Giovanna
Fasola, Salvatore
Alessandro, Riccardo
Seidita, Gregorio
Viegi, Giovanni
La Grutta, Stefania
author_sort Sottile, Gianluca
collection PubMed
description Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10–15 years. Overall, our findings reveal the importance of different genetic variants at 4p14, 16p12.1, 17q12, 6p12.2 and 17q21.1, identifying possible candidate genes responsible for susceptibility to asthma and rhino-conjunctivitis.
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spelling pubmed-63344512019-01-23 An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children Sottile, Gianluca Ferrante, Giuliana Torregrossa, Marta Cibella, Fabio Cilluffo, Giovanna Fasola, Salvatore Alessandro, Riccardo Seidita, Gregorio Viegi, Giovanni La Grutta, Stefania Ital J Pediatr Letter to the Editor Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10–15 years. Overall, our findings reveal the importance of different genetic variants at 4p14, 16p12.1, 17q12, 6p12.2 and 17q21.1, identifying possible candidate genes responsible for susceptibility to asthma and rhino-conjunctivitis. BioMed Central 2019-01-15 /pmc/articles/PMC6334451/ /pubmed/30646946 http://dx.doi.org/10.1186/s13052-019-0603-4 Text en © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Sottile, Gianluca
Ferrante, Giuliana
Torregrossa, Marta
Cibella, Fabio
Cilluffo, Giovanna
Fasola, Salvatore
Alessandro, Riccardo
Seidita, Gregorio
Viegi, Giovanni
La Grutta, Stefania
An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children
title An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children
title_full An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children
title_fullStr An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children
title_full_unstemmed An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children
title_short An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children
title_sort association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of sicilian children
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334451/
https://www.ncbi.nlm.nih.gov/pubmed/30646946
http://dx.doi.org/10.1186/s13052-019-0603-4
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