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Female underactive bladder – Current status and management

Underactive bladder (UAB) is defined by the International Continence Society as a symptom complex characterized by a slow urinary stream, hesitancy, and straining to void, with or without a feeling of incomplete bladder emptying sometimes with storage symptoms. Until recently, the topic has received...

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Autores principales: Yamany, Tammer, Elia, Marlie, Lee, Jason Jihoon, Singla, Ajay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334577/
https://www.ncbi.nlm.nih.gov/pubmed/30692720
http://dx.doi.org/10.4103/iju.IJU_306_18
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author Yamany, Tammer
Elia, Marlie
Lee, Jason Jihoon
Singla, Ajay K.
author_facet Yamany, Tammer
Elia, Marlie
Lee, Jason Jihoon
Singla, Ajay K.
author_sort Yamany, Tammer
collection PubMed
description Underactive bladder (UAB) is defined by the International Continence Society as a symptom complex characterized by a slow urinary stream, hesitancy, and straining to void, with or without a feeling of incomplete bladder emptying sometimes with storage symptoms. Until recently, the topic has received little attention in the literature probably due to a lack of consistent definitions and diagnostic criteria. We performed a literature review to identify articles related to the diagnosis and management of UAB, specifically in female patients. UAB is a common clinical entity, occurring in up to 45% of females depending on definitions used. Prevalence increases significantly in elderly women and women who live in long-term care facilities. The exact etiology and pathophysiology for developing UAB is unknown, though it is likely a multifactorial process with contributory neurogenic, cardiovascular, and idiopathic causes. There are currently no validated questionnaires for diagnosing or monitoring treatment for patients with UAB. Management options for females with UAB remain limited, with clean intermittent catheterization, the most commonly used. No pharmacotherapies have consistently been proven to be beneficial. Neuromodulation has had the most promising results in terms of symptom improvement, with newer technologies such as stem-cell therapy and gene therapy requiring more evidence before widespread use. Although UAB has received increased recognition and has been a focus of research in recent years, there remains a lack of diagnostic and therapeutic tools. Future research goals should include the development of targeted therapeutic interventions based on pathophysiologic mechanisms and validated diagnostic questionnaires.
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spelling pubmed-63345772019-01-28 Female underactive bladder – Current status and management Yamany, Tammer Elia, Marlie Lee, Jason Jihoon Singla, Ajay K. Indian J Urol Review Article Underactive bladder (UAB) is defined by the International Continence Society as a symptom complex characterized by a slow urinary stream, hesitancy, and straining to void, with or without a feeling of incomplete bladder emptying sometimes with storage symptoms. Until recently, the topic has received little attention in the literature probably due to a lack of consistent definitions and diagnostic criteria. We performed a literature review to identify articles related to the diagnosis and management of UAB, specifically in female patients. UAB is a common clinical entity, occurring in up to 45% of females depending on definitions used. Prevalence increases significantly in elderly women and women who live in long-term care facilities. The exact etiology and pathophysiology for developing UAB is unknown, though it is likely a multifactorial process with contributory neurogenic, cardiovascular, and idiopathic causes. There are currently no validated questionnaires for diagnosing or monitoring treatment for patients with UAB. Management options for females with UAB remain limited, with clean intermittent catheterization, the most commonly used. No pharmacotherapies have consistently been proven to be beneficial. Neuromodulation has had the most promising results in terms of symptom improvement, with newer technologies such as stem-cell therapy and gene therapy requiring more evidence before widespread use. Although UAB has received increased recognition and has been a focus of research in recent years, there remains a lack of diagnostic and therapeutic tools. Future research goals should include the development of targeted therapeutic interventions based on pathophysiologic mechanisms and validated diagnostic questionnaires. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6334577/ /pubmed/30692720 http://dx.doi.org/10.4103/iju.IJU_306_18 Text en Copyright: © 2019 Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Yamany, Tammer
Elia, Marlie
Lee, Jason Jihoon
Singla, Ajay K.
Female underactive bladder – Current status and management
title Female underactive bladder – Current status and management
title_full Female underactive bladder – Current status and management
title_fullStr Female underactive bladder – Current status and management
title_full_unstemmed Female underactive bladder – Current status and management
title_short Female underactive bladder – Current status and management
title_sort female underactive bladder – current status and management
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334577/
https://www.ncbi.nlm.nih.gov/pubmed/30692720
http://dx.doi.org/10.4103/iju.IJU_306_18
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