Neuroprotective effect of Notch pathway inhibitor DAPT against focal cerebral ischemia/reperfusion 3 hours before model establishment

As an inhibitor of the Notch signaling pathway, N-[N-(3,5-difluorohenacetyl)-l-alanyl]-S-phenylglycine tert-butyl ester (DAPT) may protect brain tissue from serious ischemic injury. This study aimed to explore neuroprotection by DAPT after cerebral ischemia/reperfusion (I/R) injury. DAPT was intrape...

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Detalles Bibliográficos
Autores principales: Wang, Jun-Jie, Zhu, Jun-De, Zhang, Xian-Hu, Long, Ting-Ting, Ge, Guo, Yu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334612/
https://www.ncbi.nlm.nih.gov/pubmed/30539813
http://dx.doi.org/10.4103/1673-5374.245469

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