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Epigenetic mechanism and target therapy of UHRF1 protein complex in malignancies

Ubiquitin-like with plant homeodomain and really interesting new gene finger domains 1 (UHRF1) functions as an epigenetic regulator recruiting PCNA, DNMT1, histone deacetylase 1, G9a, SuV39H, herpes virus-associated ubiquitin-specific protease, and Tat-interactive protein by multiple corresponding d...

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Detalles Bibliográficos
Autores principales: Xue, Busheng, Zhao, Jiansong, Feng, Penghui, Xing, Jia, Wu, Hongliang, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334784/
https://www.ncbi.nlm.nih.gov/pubmed/30666134
http://dx.doi.org/10.2147/OTT.S192234