Cargando…
Epigenetic mechanism and target therapy of UHRF1 protein complex in malignancies
Ubiquitin-like with plant homeodomain and really interesting new gene finger domains 1 (UHRF1) functions as an epigenetic regulator recruiting PCNA, DNMT1, histone deacetylase 1, G9a, SuV39H, herpes virus-associated ubiquitin-specific protease, and Tat-interactive protein by multiple corresponding d...
Autores principales: | Xue, Busheng, Zhao, Jiansong, Feng, Penghui, Xing, Jia, Wu, Hongliang, Li, Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334784/ https://www.ncbi.nlm.nih.gov/pubmed/30666134 http://dx.doi.org/10.2147/OTT.S192234 |
Ejemplares similares
-
The UHRF protein family in epigenetics, development, and carcinogenesis
por: UNOKI, Motoko, et al.
Publicado: (2022) -
Natural and Synthetic Anticancer Epidrugs Targeting the Epigenetic Integrator UHRF1
por: Ashraf, Waseem, et al.
Publicado: (2023) -
Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance
por: Vaughan, Robert M, et al.
Publicado: (2018) -
Novel role of UHRF1 in the epigenetic repression of the latent HIV-1
por: Verdikt, Roxane, et al.
Publicado: (2022) -
The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer
por: Ashraf, Waseem, et al.
Publicado: (2017)