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ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery

Transport of proteins across membranes is a fundamental process, achieved in every cell by the ‘Sec’ translocon. In prokaryotes, SecYEG associates with the motor ATPase SecA to carry out translocation for pre-protein secretion. Previously, we proposed a Brownian ratchet model for transport, whereby...

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Detalles Bibliográficos
Autores principales:	Corey, Robin A, Ahdash, Zainab, Shah, Anokhi, Pyle, Euan, Allen, William J, Fessl, Tomas, Lovett, Janet E, Politis, Argyris, Collinson, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335059/ https://www.ncbi.nlm.nih.gov/pubmed/30601115 http://dx.doi.org/10.7554/eLife.41803

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