ω‐6 and ω‐9 polyunsaturated fatty acids with double bonds near the carboxyl head have the highest affinity and largest effects on the cardiac I(K) (s) potassium channel

AIM: The I(K) (s) channel is important for termination of the cardiac action potential. Hundreds of loss‐of‐function mutations in the I(K) (s) channel reduce the K(+) current and, thereby, delay the repolarization of the action potential, causing Long QT Syndrome. Long QT predisposes individuals to...

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Detalles Bibliográficos
Autores principales: Bohannon, Briana M., Perez, Marta E., Liin, Sara I., Larsson, Hans Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cardiovascular Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335172/
https://www.ncbi.nlm.nih.gov/pubmed/30184322
http://dx.doi.org/10.1111/apha.13186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335172/
https://www.ncbi.nlm.nih.gov/pubmed/30184322
http://dx.doi.org/10.1111/apha.13186

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