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ω‐6 and ω‐9 polyunsaturated fatty acids with double bonds near the carboxyl head have the highest affinity and largest effects on the cardiac I(K) (s) potassium channel
AIM: The I(K) (s) channel is important for termination of the cardiac action potential. Hundreds of loss‐of‐function mutations in the I(K) (s) channel reduce the K(+) current and, thereby, delay the repolarization of the action potential, causing Long QT Syndrome. Long QT predisposes individuals to...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335172/ https://www.ncbi.nlm.nih.gov/pubmed/30184322 http://dx.doi.org/10.1111/apha.13186 |