Development of L-Asparaginase Biobetters: Current Research Status and Review of the Desirable Quality Profiles

L-Asparaginase (ASNase) is a vital component of the first line treatment of acute lymphoblastic leukemia (ALL), an aggressive type of blood cancer expected to afflict over 53,000 people worldwide by 2020. More recently, ASNase has also been shown to have potential for preventing metastasis from soli...

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Detalles Bibliográficos
Autores principales: Brumano, Larissa Pereira, da Silva, Francisco Vitor Santos, Costa-Silva, Tales Alexandre, Apolinário, Alexsandra Conceição, Santos, João Henrique Picado Madalena, Kleingesinds, Eduardo Krebs, Monteiro, Gisele, Rangel-Yagui, Carlota de Oliveira, Benyahia, Brahim, Junior, Adalberto Pessoa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335324/
https://www.ncbi.nlm.nih.gov/pubmed/30687702
http://dx.doi.org/10.3389/fbioe.2018.00212

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