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Imbalance of NET and Alpha-1-Antitrypsin in Tuberculosis Patients Is Related With Hyper Inflammation and Severe Lung Tissue Damage

Background: Pulmonary tuberculosis (PTB) can lead to lung tissue damage (LTD) and compromise the pulmonary capacity of TB patients that evolve to severe PTB. The molecular mechanisms involved in LTD during anti-tuberculous treatment (ATT) remain poorly understood. Methods and findings: We evaluated...

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Detalles Bibliográficos
Autores principales: de Melo, Mayla Gabryele Miranda, Mesquita, Eliene Denites Duarte, Oliveira, Martha M., da Silva-Monteiro, Caio, Silveira, Anna K. A., Malaquias, Thiago S., Dutra, Tatiana C. P., Galliez, Rafael M., Kritski, Afrânio L., Silva, Elisangela C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335334/
https://www.ncbi.nlm.nih.gov/pubmed/30687336
http://dx.doi.org/10.3389/fimmu.2018.03147