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Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528

Single-molecule cytoplasmic dynein function is well understood, but there are major gaps in mechanistic understanding of cellular dynein regulation. We reported a mode of dynein regulation, force adaptation, where lipid droplets adapt to opposition to motion by increasing the duration and magnitude...

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Detalles Bibliográficos
Autores principales:	Chapman, Dail E., Reddy, Babu J. N., Huy, Bunchhin, Bovyn, Matthew J., Cruz, Stephen John S., Al-Shammari, Zahraa M., Han, Han, Wang, Wenqi, Smith, Deanna S., Gross, Steven P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335402/ https://www.ncbi.nlm.nih.gov/pubmed/30651536 http://dx.doi.org/10.1038/s41467-018-08110-z

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