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Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells

There are no conventional lymphatic vessels within the CNS parenchyma, although it has been hypothesized that lymphatics near the cribriform plate or dura maintain fluid homeostasis and immune surveillance during steady-state conditions. However, the role of these lymphatic vessels during neuroinfla...

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Detalles Bibliográficos
Autores principales: Hsu, Martin, Rayasam, Aditya, Kijak, Julie A., Choi, Yun Hwa, Harding, Jeffrey S., Marcus, Sarah A., Karpus, William J., Sandor, Matyas, Fabry, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335416/
https://www.ncbi.nlm.nih.gov/pubmed/30651548
http://dx.doi.org/10.1038/s41467-018-08163-0