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A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing

Gene regulatory mechanisms rely on a complex network of RNA processing factors to prevent untimely gene expression. In fission yeast, the highly conserved ortholog of human ERH, called Erh1, interacts with the YTH family RNA binding protein Mmi1 to form the Erh1-Mmi1 complex (EMC) implicated in game...

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Detalles Bibliográficos
Autores principales: Xie, Guodong, Vo, Tommy V., Thillainadesan, Gobi, Holla, Sahana, Zhang, Beibei, Jiang, Yiyang, Lv, Mengqi, Xu, Zheng, Wang, Chongyuan, Balachandran, Vanivilasini, Shi, Yunyu, Li, Fudong, Grewal, Shiv I. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335422/
https://www.ncbi.nlm.nih.gov/pubmed/30651569
http://dx.doi.org/10.1038/s41467-018-08273-9