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Cisplatin-induced vestibular hair cell lesion-less damage at high doses
Cisplatin, a widely used anticancer drug, damages hair cells in cochlear organotypic cultures at low doses, but paradoxically causes little damage at high doses resulting in a U-shaped dose-response function. To determine if the cisplatin dose-response function for vestibular hair cells follows a si...
Autores principales: | Ding, Dalian, Jiang, Haiyan, Zhang, Jianhui, Xu, Xianrong, Qi, Weidong, Shi, Haibo, Yin, Shankai, Salvi, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese PLA General Hospital
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335437/ https://www.ncbi.nlm.nih.gov/pubmed/30671086 http://dx.doi.org/10.1016/j.joto.2018.08.002 |
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